FAQs

Who are the original ORAC developers?
The methodology of ORAC was originally developed by Dr. Guohua Cao of the National Institute of Aging in 1992 . In 1995, Dr. Cao jointed with Dr. Ronald L. Prior's group at Jean Mayer USDA Human Nutrition Research Center on Aging, where Drs. Cao and Prior were instrumental in semi-automating the ORAC assay . Since then, the ORAC assay has been extensively utilized in the field of antioxidants and oxidative stress 1,2,3,4.

1 Ehlenfeldt, M. K.; Prior, R. L. Oxygen radical absorbance capacity (ORAC) and phenolic and anthocyanin concentrations in fruit and leaf tissues of highbush blueberry. J. Agric. Food Chem. 2001, 49, 2222-2227

2 Cao, G.; Sanchez-Moreno, C.; Prior, R. L. Procyanidins, anthocyanins and antioxidant capacity in wines. Faseb J. 2000, 14, A564-A564.

3 Cao, G. H.; Shukitt-Hale, B.; Bickford, P. C.; Joseph, J. A.; McEwen, J.; Prior, R. L. Hyperoxia-induced changes in antioxidant capacity and the effect of dietary antioxidants. J. Appl. Physiol. 1999, 86, 1817-1822.

4 Cao, G. H.; Booth, S. L.; Sadowski, J. A.; Prior, R. L. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am. J. Clin. Nutr. 1998, 68, 1081-1087.

5 Cao, G. H.; Prior, R. L.; Cutler, R. G.; Yu, B. P. Effect of dietary restriction on serum antioxidant capacity in rats. Arch. Gerontol. Geriatr. 1997, 25, 245-253.


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What does "ORAC" stand for?
Who are the original ORAC developers?
What is the principle of the ORAC assay?
What does the ORAC assay actually measure?
What are the drawbacks of the original ORAC method?
What improvement on ORAC was made by Brunswick Laboratories?
Do you have literature references about the use of fluorescein for the ORAC assay?
How many harmful reactive oxygen species exist in the body?
Does the improved ORAC assay measure the total antioxidant activity against all the radicals?
What samples can be tested for ORAC?
What are the Applications of ORAC:
How long does the test take to perform?
What is the standard used in the ORAC assay?
What is the unit of the ORAC result?
Can I use the ORAC result as a quality control for my product development?
Can I use the published ORAC data for comparison purpose?
Why the ORAC assay is advantageous over many other methods?
What are the potential interferences/ pitfalls of this assay?
What instrument is used for the ORAC assay?
Who are the competitors for the ORAC testing service?
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