Who are the original ORAC developers?
The methodology of ORAC was originally developed by Dr. Guohua Cao of the National Institute of Aging in 1992 . In 1995, Dr. Cao jointed with Dr. Ronald L. Prior's group at Jean Mayer USDA Human Nutrition Research Center on Aging, where Drs. Cao and Prior were instrumental in semi-automating the ORAC assay . Since then, the ORAC assay has been extensively utilized in the field of antioxidants and oxidative stress 1,2,3,4.
1 Ehlenfeldt, M. K.; Prior, R. L. Oxygen radical absorbance capacity (ORAC) and phenolic and anthocyanin concentrations in fruit and leaf tissues of highbush blueberry. J. Agric. Food Chem. 2001, 49, 2222-2227
2 Cao, G.; Sanchez-Moreno, C.; Prior, R. L. Procyanidins, anthocyanins and antioxidant capacity in wines. Faseb J. 2000, 14, A564-A564.
3 Cao, G. H.; Shukitt-Hale, B.; Bickford, P. C.; Joseph, J. A.; McEwen, J.; Prior, R. L. Hyperoxia-induced changes in antioxidant capacity and the effect of dietary antioxidants. J. Appl. Physiol. 1999, 86, 1817-1822.
4 Cao, G. H.; Booth, S. L.; Sadowski, J. A.; Prior, R. L. Increases in human plasma antioxidant capacity after consumption of controlled diets high in fruit and vegetables. Am. J. Clin. Nutr. 1998, 68, 1081-1087.
5 Cao, G. H.; Prior, R. L.; Cutler, R. G.; Yu, B. P. Effect of dietary restriction on serum antioxidant capacity in rats. Arch. Gerontol. Geriatr. 1997, 25, 245-253.
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