Brunswick Labs provides biological analysis using human cells as a test model to evaluate the anti-aging properties of a material. The cellular assay uses SIRT1 as a biomarker for aging process.
SIRT1 is a protein that is believed to play important roles in longevity and age-related diseases. Previous studies have shown that when cells age, SIRT1 expression decreases, while induction and activation of SIRT1 have been associated with extended life span. These studies have triggered the search for SIRT1 activators that may be used as dietary supplements to promote health and longevity.
The Cellular Anti-aging Assay (SIRT1 assay) determines the ability of a test material to stimulate SIRT1 protein expression or activity in human cells, which translates to the material’s anti-aging potential.